Oxandrolone is most certainly a hepatotoxic steroid. It does not carry the strongest level of hepatotoxicity among anabolic steroids, but it is stronger than most. This is due to it being a C17-aa anabolic steroid. All C17-aa steroids are hepatic, but the level of toxicity varies greatly between them. Due to this steroid’s strong hepatotoxicity, this is why total use must be limited (see administration section).
Due to use, those who supplement with Anadrol will find their liver enzyme values increase. An increase in values is not a sign of damage but rather a sign of stress that can lead to damage if responsible practices are not followed and the stress is allowed to remain. Proper dosing and duration of use protocols are imperative when it comes to this steroid. Further, it is important the individual avoids excess alcohol consumption when supplementing with this steroid due to the liver stress such consumption will cause. In fact, most will find avoiding all alcohol to be best during use. If this is a problem and you are supplementing for the purpose of performance enhancement remember there is nothing on earth that is as anti-performance as alcohol. Those who supplement are also encouraged to limit their use of Over the Counter (OTC) medications. Many OTC medications carry strong hepatic natures, and the added stress can be extensive when coupled with Anadrol. Use should be limited to when only absolutely needed. If these rules can be followed, once use is discontinued liver enzyme values will return to normal and no damage will be done. As a final note, Anadrol should not be used if the liver is unhealthy.
We've already discussed this steroids strong hepatotoxic nature above, and as such, caution must be applied. Beyond this factor, like all DHT anabolic steroids Anadrol 50 will not aromatize; however, for reasons that are to this day still somewhat of a mystery it will carry strong estrogenic properties. Those who supplement with Anadrol 50 can fall prey to Gynecomastia, massive increases in blood pressure, and of course, water retention as discussed above. Each and every one of these adverse reactions can occur, and in a significant fashion, but for the healthy adult male, all hope is not lost; far from it. To combat such issues, those who supplement with Anadrol 50 will find the use of aromatase inhibitors (AI's) to be tremendously beneficial; the same AI's we often use to combat aromatizing steroids. Further, living a lifestyle that promotes a healthy blood pressure is imperative, as well as making sure you're not overeating abundantly; especially carbohydrates. If you can do these things, assuming you had a healthy blood pressure to begin with you will enjoy successful supplementation; it should go without saying, those who have preexisting high blood pressure should not supplement.