Fetal/Neonatal Anomalies and Mortality:
Uncommon (% to 1%): Congenital heart lesions, down syndrome, club foot, congenital gut lesions, hypospadias, microcephaly, harelip and cleft palate, congenital hip, hemangioma, undescended testicles, polydactyly, conjoined twins and teratomatous malformation, patent ductus arteriosus, amaurosis, arteriovenous fistula, inguinal hernia, umbilical hernia, syndactyly, pectus excavatum, myopathy, dermoid cyst of scalp, omphalocele, spina bifida occulta, ichthyosis, and persistent lingual frenulum, neonatal death, fetal death/stillbirth
Postmarketing reports: Skeletal malformations of the skull, face, nasal passages, jaw, hand, limb (ectromelia including amelia, hemimelia, and phocomelia), foot (clubfoot), spine, joints; septal heart defects, muscular ventricular septal defect, patent ductus arteriosus, tetralogy of Fallot, coarctation of the aorta; down syndrome; ear abnormalities and deafness; cleft lip and palate, imperforate anus, tracheoesophageal fistula, diaphragmatic hernia, omphalocele; hypospadias, cloacal exstrophy, lung tissue malformations; malformations of the eye and lens (cataract); neuroectodermal tumor, thyroid tumor, hepatoblastoma, lymphocytic leukemia; neural tube defects (anencephaly, meningomyelocele), microcephaly, hydrocephalus; renal agenesis and renal dysgenesis; dwarfism, mental retardation
Neoplasms: Liver (hepatic hemangiosarcoma, liver cell adenoma, hepatocellular carcinoma ); breast (fibrocystic disease, breast carcinoma); endometrium (endometrial carcinoma); nervous system ( astrocytoma , pituitary tumor, prolactinoma, neurofibromatosis , glioblastoma multiforme , brain abcess); ovary (luteoma of pregnancy, dermoid cyst of the ovary , ovarian carcinoma); trophoblastic (hydatiform mole, choriocarcinoma ); miscellaneous ( melanoma , myeloma , perianal cysts, renal cell carcinoma , Hodgkin's lymphoma, tongue carcinoma, bladder carcinoma)
However, the Anavar steroid was discontinued by Searle in 1989, due to the bad press brought on by bodybuilders abusing the drug. It was later reintroduced to the world market as Oxandrin in 1995, but it remains a controlled substance under US law. The current manufacturer of oxandrolone holds all the rights to their medicine, and that’s why it is very rare to find oxandrolone today. It’s still called Anavar by most people, and it’s very hard to buy. Even if you do find Anavar for sale, the law of supply and demand inevitably results in a rather exorbitant price for the steroid.